Diethylene glycol bis(p-toluenesulfonate)
CAS No. 7460-82-4
Diethylene glycol bis(p-toluenesulfonate) ( Diethylene glycol di(p-toluenesulfonate); Bis-Tos-PEG2 )
产品货号. M26939 CAS No. 7460-82-4
Diethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
1G | ¥292 | 有现货 |
|
生物学信息
-
产品名称Diethylene glycol bis(p-toluenesulfonate)
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Diethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
-
产品描述Diethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
同义词Diethylene glycol di(p-toluenesulfonate); Bis-Tos-PEG2
-
通路Others
-
靶点Other Targets
-
受体Human Endogenous Metabolite; phosphoglucose isomerase (PGI)
-
研究领域——
-
适应症——
化学信息
-
CAS Number7460-82-4
-
分子量414.5
-
分子式C18H22O7S2
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCc1ccc(cc1)S(=O)(=O)OCCOCCOS(=O)(=O)c1ccc(C)cc1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Gaitonde MK, et al. Effect of 6-phosphogluconate on phosphoglucose isomerase in rat brain in vitro and in vivo. J Neurochem. 1989 May;52(5):1348-52.
产品手册
关联产品
-
Platycodigenin
Platycodigenin isolated from platycodon grandiflorum, has in vitro anti-proliferative activity against the HSC-T6 cell line.
-
PLpro inhibitor
PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM).
-
(R)-P7C3-Ome
P7C3 is a drug related to latrepirdine (dimebon), which has neuroprotective and proneurogenic effects, and may be potentially useful for the treatment of Alzheimer's disease and similar neurodegenerative disorders.